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Quick Facts
- The Bob Allison Ataxia Research Center (BAARC) at the University
of Minnesota is a comprehensive program for basic science research,
clinical studies, and education in the disease of the nervous system
that causes ataxia and related disorders.
- Currently as many as 150,000 Americans suffer from some form
of ataxia - three times the number of individuals who suffer from
Lou Gehrig's disease (ALS). Twenty five percent of ataxias are
hereditary, a proportion that is higher than some of the other
neurodegenerative diseases. To date there is no known cure.
- Bob Allison may be the most identifiable casualty of ataxia.
He was diagnosed after retiring from a legendary baseball career
with the Washington Senators and Minnesota Twins. Early efforts
at finding answers about ataxia benefitted from Bob Allison's immense
dedication, and the research center that bears his name was born.
On April 10, 1995, Bob Allison died in Rio Verde, Arizona, at the
age of 60.
- In 1990, Bob Allison helped found the Bob Allison Ataxia Research
Center at the University of Minnesota. Bob's efforts were joined
by his wife Betty, sons Mark, Kirk, Kyle, former teammate Jim Kaat,
and former Twins teammate and manager Frank Quilici. This group
founded the Center, determined its mission and course, and both
planned and implemented fundraising efforts, in cooperation with
researchers at the University of Minnesota.
- In 1993, Dr. Harry Orr of the University of Minnesota and Dr.
Huba Zoghbi at the Baylor College of Medicine in Houston, Texas,
identified the gene (SCA1) responsible for a hereditary form of
ataxia. They also discovered that the gene has a genetic flaw,
a mutation consisting of an abnormal repetition of three-letter
segments of the genetic code causing a kind of typographical error
in the genetic code. They further discovered that this type of
mutation is common to other inherited neurological disorders as
well as some cancers.
- Dr. Harry Orr has also genetically engineered a mouse strain
of ataxia to study how a specific gene produces a protein that
kills brain cells.
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